Conference Proceedings

Baseline grey matter volume of non-transitioned "ultra high risk" for psychosis individuals with and without attenuated psychotic symptoms at long-term follow-up

VL Cropley, A Lin, B Nelson, RLEP Reniers, AR Yung, CF Bartholomeusz, P Klauser, D Velakoulis, P McGorry, SJ Wood, C Pantelis

Schizophrenia Research | Published : 2016

Abstract

Introduction: Two thirds of individuals identified as ultra-high risk (UHR) for psychosis do not transition to psychosis over the medium to long-term (non-transition; UHR-NT). Nevertheless, many of these individuals have persistent attenuated psychotic symptoms (APS). The current study examined whether there were differences in baseline grey matter volume (i.e. at initial identification as UHR) in UHR-NT individuals whom had APS compared to those without APS (No-APS) at medium to long-term follow-up. Methods: Participants were help-seeking individuals who were identified as being at UHR for psychosis between 2 and 12 years previously (mean = 7.5). The sample consisted of 109 participants who..

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